Monday, February 20, 2012

4 diseases causing pain-sinus

4 diseases causing pain-sinus

Pain in sinus is generally attributed to sinusitis. However, granulomatous inflammation and sinonasal malignancies may also trigger the pain.
Churg Strauss Syndrome (CSS)
CSS, the allergic angiitis, is the granulomatous inflammation of the vessels of lungs, peripheral nerves and skin. The patients suffering from asthma and rhinitis are prone to the syndrome. It may lead to chronic or acute paranasal sinus pain. Other symptoms of the syndrome include polyposis, rhinitis and the sinus’ opacification on radiograph.

Sinusitis related pain may be a result of the pressure change, inflammation and / or blockage of the sinuses. To study the pain-sinus, heat, cold and electric probe stimulation has been used. The studies concluded that the mucosa lining the ostia (nasal opening) of the paranasal sinuses is the most pain prone region. Some times pain is associated with the sinus cavity, but the mucosal cavity located in the sinus is not very sensitive to pain.
Sinonasal cancers and tumors
The sinonasal cancers and tumors affect the nasal cavity and paranasal sinuses. The sinonasal tumors are generally diagnosed in the advance stage as no significant symptoms or signs appear in the early stages. The cancer and tumor symptoms are similar to that of sinus disease symptoms, such as nasal discharge and pain in the sinuses. The most common sinonasal malignancy is maxillary sinus carcinoma. The ethmoid sinus is the second most common place where tumors and cancers develop.
Wegener’s granulomatosis (WG)
The paranasal sinuses host a wide range of granulomatous conditions that are rare but could be risky. For instance, Wegener’s granulomatosis. Wegener’s, a rare medical condition, involves vasculitis of the nasal mucosa, the sinus and the respiratory tract, and granulomatous inflammation. If recurrent or chronic sinusitis patients have concurrent cutaneous, pulmonary or renal abnormalities, or inflammation of the nasal septa, they should be examined for Wegener’s signs. Wegener’s granulomatosis may lead to the pain-sinus. Clinical features of the WG include bloody or purulent nasal discharge, perforation in the nasal septa and the nose deformity. WG patients are administered cyclophosphamide and prednisone.

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